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Shinichi Uchida Selected Research

Nephrogenic Diabetes Insipidus

1/2022Congenital nephrogenic diabetes insipidus presenting as osmotic demyelination syndrome in infancy: A case report.
12/2018AKAPs-PKA disruptors increase AQP2 activity independently of vasopressin in a model of nephrogenic diabetes insipidus.
6/2018Activation of AQP2 water channels without vasopressin: therapeutic strategies for congenital nephrogenic diabetes insipidus.
11/2016Wnt5a induces renal AQP2 expression by activating calcineurin signalling pathway.
6/2013Hereditary nephrogenic diabetes insipidus in Japanese patients: analysis of 78 families and report of 22 new mutations in AVPR2 and AQP2.
5/2007A case of nephrogenic diabetes insipidus with a novel missense mutation in the AVPR2 gene.
9/2006Pathogenesis and treatment of autosomal-dominant nephrogenic diabetes insipidus caused by an aquaporin 2 mutation.
12/2003A case of a novel mutant vasopressin receptor-dependent nephrogenic diabetes insipidus with bilateral non-obstructive hydronephrosis in a middle aged man: differentiation from aquaporin-dependent nephrogenic diabetes insipidus by response of factor VII and von Willebrand factor to 1-diamino-8-arginine vasopressin administration.
1/2003Successful treatment of partial nephrogenic diabetes insipidus with thiazide and desmopressin.
2/2002Water intake and 24-hour blood pressure monitoring in a patient with nephrogenic diabetes insipidus caused by a novel mutation of the vasopressin V2R gene.

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Shinichi Uchida Research Topics

Disease

34Pseudohypoaldosteronism
11/2020 - 12/2005
32Hypertension (High Blood Pressure)
01/2021 - 12/2005
12Hyperkalemia
01/2020 - 07/2005
11Chronic Renal Insufficiency
05/2021 - 03/2012
10Nephrogenic Diabetes Insipidus
01/2022 - 02/2002
9Renal Insufficiency (Renal Failure)
06/2022 - 01/2016
7Gitelman Syndrome
01/2022 - 11/2010
6Inborn Genetic Diseases (Disease, Hereditary)
01/2022 - 06/2013
6Hypokalemia
01/2022 - 10/2009
6Nephrotic Syndrome (Syndrome, Nephrotic)
01/2021 - 03/2003
5Bartter Syndrome (Syndrome, Bartter)
10/2021 - 08/2002
4Fibrosis (Cirrhosis)
05/2021 - 10/2017
4Proteinuria
01/2021 - 10/2011
4Infections
06/2020 - 01/2017
4Metabolic Syndrome (Dysmetabolic Syndrome X)
01/2020 - 10/2012
4Alkalosis
01/2019 - 10/2009
4Acidosis
06/2016 - 10/2006
3Brain Diseases (Brain Disorder)
01/2022 - 01/2015
3Polyuria
04/2021 - 06/2018
3Cognitive Dysfunction
07/2019 - 09/2010
3Albuminuria
01/2019 - 10/2017
3Anemia
12/2018 - 02/2011
3Hypertrophy
01/2018 - 04/2005
3Glomerulonephritis
01/2017 - 10/2011
3Ischemia
11/2012 - 12/2005
3Hypotension (Low Blood Pressure)
12/2010 - 10/2009
2Hypernatremia
01/2022 - 04/2021
2Hyperaldosteronism (Conn Syndrome)
01/2022 - 05/2020
2Inflammation (Inflammations)
05/2021 - 01/2018
2Hypercalcemia (Milk Alkali Syndrome)
04/2021 - 01/2010
2Hyperparathyroidism
04/2021 - 03/2012
2Interstitial Nephritis (Tubulointerstitial Nephritis)
01/2021 - 06/2013
2Nephritis
06/2020 - 01/2017
2Autosomal Dominant Polycystic Kidney (ADPKD)
01/2020 - 01/2019
2Amnesia (Dissociative Amnesia)
07/2019 - 12/2018
2Bacteremia
06/2019 - 11/2018
2Heart Diseases (Heart Disease)
01/2019 - 02/2011
2Atherosclerosis
12/2018 - 12/2017
2Heart Failure
12/2018 - 01/2017
2Hemorrhage
05/2018 - 01/2018
2Cysts
01/2018 - 01/2014
2Diabetes Mellitus
01/2018 - 01/2018

Drug/Important Bio-Agent (IBA)

29Phosphotransferases (Kinase)IBA
01/2020 - 10/2006
20SaltsIBA
10/2021 - 11/2010
20Lysine (L-Lysine)FDA Link
01/2020 - 12/2008
17Proteins (Proteins, Gene)FDA Link
01/2022 - 06/2002
12SodiumIBA
01/2022 - 10/2012
9Alanine (L-Alanine)FDA Link
01/2020 - 11/2010
9Proline (L-Proline)FDA Link
01/2020 - 11/2010
6DiureticsIBA
01/2022 - 09/2015
6Cullin Proteins (Cullins)IBA
11/2020 - 07/2013
6Member 3 Solute Carrier Family 12IBA
01/2019 - 01/2013
6Vasopressins (Vasopressin)IBA
01/2019 - 02/2002
5Pharmaceutical PreparationsIBA
01/2021 - 10/2011
5PotassiumIBA
01/2020 - 07/2005
5ChloridesIBA
01/2019 - 12/2015
5CreatinineIBA
01/2019 - 04/2010
4Vasopressin Receptors (Arginine Vasopressin Receptor)IBA
01/2022 - 02/2002
4CalciumIBA
04/2021 - 01/2010
4AlbuminsIBA
01/2021 - 08/2016
4Sodium Chloride SymportersIBA
01/2020 - 12/2005
4Aquaporins (Water Channels)IBA
06/2018 - 12/2003
4ThiazidesIBA
01/2016 - 01/2003
3Parathyroid Hormone (Parathormone)IBA
04/2021 - 08/2016
3AldosteroneIBA
01/2020 - 09/2014
3Antihypertensive Agents (Antihypertensives)IBA
01/2020 - 07/2013
3Immunoglobulin G (IgG)IBA
06/2019 - 01/2017
3AntibodiesIBA
06/2019 - 11/2013
3Hemoglobins (Hemoglobin)IBA
12/2018 - 07/2013
3Biomarkers (Surrogate Marker)IBA
12/2017 - 12/2005
3ElectrolytesIBA
02/2017 - 11/2010
3Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
11/2015 - 09/2013
3Angiotensin IIIBA
09/2014 - 06/2013
3Aquaporin 2IBA
06/2013 - 09/2006
3Glycerol (Glycerine)FDA LinkGeneric
08/2006 - 04/2005
2Adenosine A2A Receptor (Adenosine A2A Receptors)IBA
04/2022 - 08/2021
2SymportersIBA
01/2022 - 05/2014
2CollagenIBA
11/2021 - 01/2018
2LipidsIBA
05/2021 - 05/2018
2Arginine Vasopressin (Argipressin)IBA
04/2021 - 06/2013
2Serum AlbuminIBA
01/2021 - 02/2017
2GlucocorticoidsIBA
01/2021 - 10/2011
2Vitamin DFDA LinkGeneric
01/2021 - 06/2017
2Phosphates (Orthophosphate)IBA
01/2021 - 08/2016
2plasmin receptorIBA
06/2020 - 01/2017
2Uric Acid (Urate)IBA
01/2020 - 01/2020
2Insulin (Novolin)FDA Link
01/2020 - 09/2015
2TolvaptanFDA Link
01/2020 - 01/2019
2Scopolamine (Hyoscine)FDA Link
07/2019 - 12/2018
2Peptides (Polypeptides)IBA
07/2019 - 12/2018
2Factor XIII (Coagulation Factor XIII)IBA
06/2019 - 06/2017
2Fibrinogen (Factor I)FDA Link
06/2019 - 06/2017
2Small Interfering RNA (siRNA)IBA
01/2018 - 03/2008
2UbiquitinIBA
01/2018 - 01/2016
2Ligases (Synthetase)IBA
01/2018 - 01/2016
2Sodium Potassium Chloride Symporter Inhibitors (Loop Diuretics)IBA
01/2018 - 01/2017

Therapy/Procedure

7Renal Dialysis (Hemodialysis)
01/2021 - 02/2011
5Therapeutics
06/2020 - 07/2013
2Protein-Restricted Diet (Diet, Protein Restricted)
01/2019 - 03/2012
2Catheters
11/2018 - 01/2018